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The mold in the room invades the brain

  • Writer: David Brisson
    David Brisson
  • Sep 15
  • 8 min read

Updated: Oct 23

If you live in a moldy room, how would you feel if that mold caused a decline in your concentration and memory?

Mold is widely recognized as an allergy trigger, producing recognizable reactions like sneezing, coughing, and asthma, but mold can have a more serious harmful effect: brain damage.

Mold reaches the brain through the nose

Inhaled mold travels through the olfactory nerves deep inside the nose and into the brain. This route of entry is particularly likely to affect the deep brain region known as the limbic system. This deep part of the brain is called the limbic system, which controls emotions and memory. When this area, which regulates anxiety, fear, emotions, memory, and instinctive behavior, is affected by inflammation and oxidative stress, it can cause a variety of symptoms. For example,

  • Forgetfulness and difficulty concentrating

  • Insomnia, nightmares, and feeling tired even after sleeping

  • Depressed mood and lack of motivation

  • Emotional restlessness, anxiety, irritability

  • I can't make decisions or organize my thoughts

Brain problems commonly referred to as brain fog (a state of having a foggy mind, feeling dizzy) are common. Insomnia, headaches, and dizziness also occur. Tinnitus and hyperacusis also occur. Bronchial symptoms such as coughing can also occur, but in general, various symptoms affect the entire head from the neck up.

Mold directly attacks the limbic system

The limbic system, located at the innermost center of the brain, is responsible for functions related to animal instincts. It is also known as the mammalian brain. In contrast to the animalistic mammalian brain, the part of the human brain that is unique to humans and responsible for reason, logic, and thought is called the cerebral cortex. The human brain is arranged in such a way that it surrounds the outer part of the limbic system. Unlike the cerebral cortex, the limbic system acts like the "roots of the mind" that supports our emotions, memories, and instinctive behavior. The limbic system is the innermost part of the brain and is made up of the following four components:

The limbic system consists of four parts: the hippocampus, amygdala, hypothalamus, and cingulate gyrus

Hippocampus: As the control center of memory, it is responsible for recording new events and consolidating them in the brain.

Amygdala: Processes emotions such as anger and fear and is responsible for the emotional accelerator and brake.

Hypothalamus: Regulates body temperature, appetite, sexual desire, and the autonomic nervous system, controlling activities necessary for survival.

Cingulate gyrus: Involved in regulating emotions and behavior, and thought to be related to the development of anxiety and depression.

When you inhale mold in your home, the first thing to be affected is the limbic system at the back of your nose. Therefore, mold and mycotoxins cause a decline in the function of the four areas mentioned above. If people continue to inhale mold daily without realizing its destructive power, it can lead to a significant decline in quality of life that goes beyond simple physical discomfort. Mold anger is a characteristic symptom of sudden outbursts of anger and rage. When mold inhalation causes chronic inflammation of the amygdala, it can also lead to brain fog, which can cause sudden outbursts of anger in the midst of disorganized conversations and slipping of words. Others may also perceive you as incoherent or unintelligible.

Damage to the limbic system can lead to memory loss, emotional instability, depression, insomnia, overeating, lethargy, decreased libido, and autonomic nervous system imbalance. MCAS and multiple chemical sensitivity also become more likely to occur. This is because the amygdala contains a large number of mast cells. The symptoms that occur in people who inhale mold toxins are related to the limbic system.

Types of mold and characteristics of rooms where they are likely to occur

A common type of mold that is commonly found indoors.

  • Aspergillus: This is the most common mold found in Japanese homes, often found inside air conditioners, bathrooms, and closets. Some species (such as A. fumigatus) produce strong mycotoxins that can cause pulmonary aspergillosis, chronic sinusitis, and encephalitis. People with weakened immune systems can develop serious, life-threatening infections.

  • Cladosporium: A type of black mold often found on window frames, closets, and curtains, known to cause allergies.

  • Penicillium: Also known as blue mold, Penicillium can grow in a variety of places, including food, tatami mats, furniture, and fabrics. It can release large numbers of spores into the air, causing respiratory symptoms to worsen.

  • Stachybotrys: This is the so-called "black mold" that hides behind damp plasterboard and wallpaper. It produces powerful mycotoxins and has been linked to fatal accidents in the United States (for example, the mass infant deaths in Ohio in the 1990s).

Mold in the environment is more likely to grow in the following conditions:

  • Indoor humidity is maintained at 40% or higher (insufficient dehumidification measures)

  • A dark place where UV rays cannot reach

  • Spaces where organic matter such as dust, fabrics, cardboard, and books is left unattended

  • Insufficient ventilation, condensation, and enclosed spaces

  • A comfortable environment with a temperature of 25-30°C

When you notice a moldy smell, the room may already be filled with spores and mold toxins.

Where does the inhaled mold go?

Brain, lungs, and intestines: three routes of invasion and their impact

Mold that grows in a room not only releases visible spores but also tiny, invisible toxins (mycotoxins) into the air. These enter our bodies through various routes, such as breathing and eating. Mycotoxins affect the body through the three main routes: the brain, lungs, and intestines.

① From the nose to the brain: olfactory nerve route


Deep inside the nose is a special pathway called the "olfactory nerve" that directly connects to the brain. This acts like a back door, allowing substances to reach the central nervous system without passing through the blood-brain barrier (BBB).

Some mycotoxins are nano-sized particles that, when inhaled, travel through the olfactory nerve pathway directly to the limbic system and hypothalamus, causing neurological symptoms such as brain fog, memory loss, anxiety, and sleep disorders.

This process can manifest as feelings that are difficult to explain, such as a heavy head, difficulty thinking, or sudden depression, which are unique to inhaling mold.

② From the airways to the whole body: Lung → Blood flow route

Inhaled spores and mycotoxins first reach the throat, bronchi and alveoli, where they irritate the mucosal cells of the respiratory tract, causing symptoms such as coughing, asthma and chronic airway inflammation.

Even more troublesome is that toxins absorbed into the blood from the lungs circulate throughout the body, causing secondary damage to organs such as the liver, kidneys, brain, and muscles. In particular, gliotoxin (derived from Candida and Aspergillus) suppresses the function of white blood cells and weakens immune function. This is why it is said to increase susceptibility to infections and the risk of cancer. Gliotoxin and ochratoxin are themselves known to be carcinogens.

3. From oral ingestion: Route from the intestines to the whole body

Mold spores and mycotoxins can reach the intestines through stale food, contaminated tap water, or unknowingly swallowing airborne spores.

In the intestines, they disrupt the balance of bacteria in the intestinal environment with destructive power. This is a condition known as dysbiosis, where the intestinal bacteria become imbalanced. Originally, 60 trillion intestinal bacteria live symbiotically in the intestines of each person, maintaining a mutual balance and protecting the body. When this state of imbalance occurs, the intestinal mucosa becomes exposed to mold toxins, unable to stop inflammation and prone to leaky gut. This causes toxins and undigested substances that normally would not enter the body to leak from the intestinal mucosa into the bloodstream. This can spread chronic inflammation throughout the body and trigger autoimmune disorders that disrupt the immune system.

Furthermore, toxins absorbed through this pathway are sent to the liver, which places a sudden increase in the burden on metabolism and excretion. Substances that are toxic to the liver and kidney, such as aflatoxins and ochratoxins, accumulate in the body if detoxification cannot keep up, leading to hepatitis, kidney damage, cancer, chronic fatigue syndrome, and hormonal imbalances.


How can I get rid of mold toxins that have entered my body?

The key lies in the cell membrane and mitochondria


The tricky thing about mycotoxins is that they are fat-soluble, so they get tangled in the lipid parts of the cell membrane structure. Because cell membranes have a two-layer structure, toxins accumulate in the niche gaps between the membranes, impairing the movement of substances that should be moving in and out of the cell, which impairs metabolism. In particular, in lipid-rich organs such as the brain and nerves, these toxins remain for long periods of time, causing the lipids to rust and leading to chronic functional disorders. Inside cells are small factories called mitochondria, which are energy power plants, and the membrane that forms the outer wall of this factory is also made of phosphatidylcholine.

The area damaged by mycotoxins, in other words, where mycotoxins accumulate, is the lipid portion of phosphatidylcholine. Therefore, when trying to remove mycotoxins, phosphatidylcholine is always involved. It replaces the damaged cell membrane, mycotoxins included, returning the cell to a toxin-free state and restoring cellular function. To ensure that the treatment reaches the brain, intravenous infusion of cell membrane components for mycotoxin treatment is used.

By repeatedly administering mycotoxin treatment intravenously, the mycotoxins that have accumulated, particularly in the cell membranes of the brain, are removed through the following mechanism:

  • Repair of nerve cell and mitochondrial membranes

  • The mycotoxins that are entangled in the lipid part of the cell membrane are completely excreted from the body.

  • Normalizing brain information transmission

  • Recovering from chronic fatigue and brain fog

What's noteworthy is that phosphatidylcholine is delivered to blood vessels throughout the body over time via intravenous infusion, cleaning all cell membranes along the way. Its ability to penetrate the blood-brain barrier, the brain's vascular barrier, ensures it eliminates mycotoxins clinging to nerve cells. The drug penetrates into gaps in cell membranes, areas that supplements cannot reach, mobilizing toxins. It's the first choice for those with chronic health problems, autism, and those with clear brain dysfunction despite no abnormalities detected in tests. It's utilized as a regenerative medicine approach, rather than merely a symptomatic treatment that suppresses or postpones symptoms. This treatment is applicable not only to mycotoxins, but also to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, electromagnetic hypersensitivity, and mast cell activation syndrome (MCAS). After eliminating mold and reducing mycotoxins through a PK protocol, stem cell-based regenerative medicine may be considered. Additionally, incorporating substances that reduce brain inflammation, such as resveratrol and curcumin, may also be an effective treatment.


Finally: Mold attacks the brain


If left unchecked, mold can penetrate deep into the brain and affect your emotions, memory, judgment, and autonomic nervous system function.

Simply installing an air purifier isn't enough. To combat indoor mold, lower the humidity level, declutter, and open the curtains to let in light. Kill mold bacteria in the body with appropriate chemicals, and address the growing mycotoxins in the body with a medical approach. Symptoms like brain fog, forgetfulness, and autonomic nervous system disorders tend to be self-resolved, attributing them to aging, menopause, stress, or lack of sleep. However, children can also develop brain fog if they continue to inhale mold. Sleeping in a moldy room is difficult. Even if you manage to get enough sleep, you may wake up with a heavy feeling in your head, a swollen face, and a sluggish feeling. Overlooking indoor mold can often lead to mental health issues.

The day you start to wonder, "Could it be mold?" is a turning point. Don't ignore it, but consult Wellness Clinic Kagurazaka, which specializes in environmental medicine. Health damage caused by mold can be prevented and even reversed with accurate information.


 
 
 

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